Salvador Sierra San Nicolas, M.D., Ph.D.
Proximity ligation assay (PLA) has become the assay of choice for demonstrating the proximity of a variety of proteins, including G Protein-Coupled Receptors (GPCRs), in cells and native tissue. Recently, this technique has been applied in native tissue to detect histone modifications in certain promoters, increasing the information (specific cells carrying the modifications) obtained by doing ChiP.
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This How-to Talks by Postdocs session is co-sponsored by the Tompkins-McCaw Library for the Health Sciences, Wright Center for Clinical and Translational Research, and VCU Postdoctoral Association. Virginia Commonwealth University is an equal opportunity/affirmative action employer.